Aqueous Extract of Anticancer Drug CRUEL Capsules Exerts Anti-Proliferative Effects in Renal Cell Carcinoma Cells

Cancer is one of the most deadly diseases for the society and one of the most challenging diseases for the scientists all over the world to tackle with. Drugs and therapies available until now are still not effective enough for most of the cancer types and have side effects. People are, therefore looking towards traditional Ayurveda system of medicine to find out relatively safe and cost effective solution for cancer treatment. Herbometallic and herbomineral therapeutics are being considered as promising alternative medicines for treatment of diseases like cancer. Rasa shastra is the branch of Ayurveda which deals with medicinal properties of herbometallic and herbomineral preparations and the drugs which are used are known as Rasa Aushadhi. These therapeutics are claimed for faster in action and more efficient as compared to only herbal drugs. Herbomineral drugs are prepared by anaerobic cooking which converts the toxic mega particles of metal into safe and efficacious nanoparticles and even smaller picoparticles explaining the usefulness of these drugs as effective medicines for cancer (Sheikh et al., 2012). Cruel Capsule is an ayurvedic proprietary medicine marketed by Virgo UAP Pharma Ltd. and UNJHA ayurvedic pharmacy India. It is a combination of antineoplastic, tissue promoting and antiinflammatory herbo-minerals. It is claimed to be useful in different type